Published retrospective studies report that venlafaxine overdose may be associated with an increased risk of fatal outcomes compared to that observed with SSRI antidepressant products, but lower than that for tricyclic antidepressants. Epidemiological studies have shown that venlafaxine treated patients have a higher burden of suicide risk factors than SSRI patients. The extent to which the finding of an increased risk of fatal outcomes can be attributed to the toxicity of venlafaxine in overdose, as opposed to some characteristics of venlafaxine-treated patients, is not clear. Prescriptions for venlafaxine should be written for the smallest quantity of the medicinal product consistent with good patient management in order to reduce the risk of overdose.
In 1997, Weller and Weller published one of the first studies to investigate when menstrual synchrony occurs in complete families. Their study was conducted in Bedouin villages in northern Israel . Twenty seven families, which had from two to seven sisters 13 years or older and collected data on menstrual cycle onsets over a three-month period. Using the methods of,  they reported menstrual synchrony occurred for the first two months, but not for the third month for roommate sisters, close friend roommates, and for families as a whole. 
If you have one or two periods with heavy or prolonged bleeding, there's probably no reason to worry. If, however, heavy bleeding (menorrhagia) recurs during three or more consecutive menstrual periods, or if you have bleeding after menopause, or the abnormal bleeding is accompanied by fever or other symptoms, consult your health care professional. Also call your health care professional if the heavy bleeding is accompanied by pain that is not relieved by ibuprofen or acetaminophen. Avoid taking aspirin because it could worsen the bleeding problem.